Cadonilimab is humanized immunoglobulin (Ig) G1 scaffold Fc-engineered monoclonal antibody against PD-1 (programmed cell death 1) and CTLA-4(cytotoxic T lymphocyte associated antigen 4), specifically, It has good application prospects for the treatment of a range of solid tumours, including cervical cancer, lung cancer, gastric/gastroesophageal junction cancer, oesophageal squamous cell cancer, liver cancer and nasopharyngeal cancer.
Product name | Cadonilimab Biosimilar |
Species | Homo sapiens |
Expression system | CHO-K1 |
Buffer | PBS, pH 7.4 |
Delivery condition | Dry ice (-80°C) |
Delivery Time | 1 week if in stock; 4 weeks if production needed |
Storage condition | Store at -80°C |
Brand | BioMetas |
Applications | ELISA, assay, in vivo |
Aliases/Synonyms | AK104, AK-104 |
Reference | |
Note | For research use only. Not suitable for clinical or therapeutic use. |
Isotype | IgG1, κ |
Clonality | Monoclonal Antibody |
Size | 1mg, 5mg, 10mg, 50mg, 100mg |
Brand | BioMetas |
Product type | Biosimilar |
Clonality | Monoclonal Antibody |
Expression system | CHOK1 |
Applications | Elisa, assay, in vivo |
Fig. 1.) 4-20% SDS-PAGE analysis
Recombinant protein was visualized by Coomassie Brilliant Blue R250 staining.
Fig. 2.) SEC-HPLC analysis
Column: Superdex 200 Increase 5/150 GL
Running buffer: 2xPBS, pH 7.4