His Kras(2-185) G12D

Description

K-Ras belongs to the small GTPase superfamily, Ras family. It is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. K-Ras functions as a molecular on/off switch. KRAS mutation occurs in nearly 30% of human cancers, while KRAS(G12D) is the most prevalent and oncogenic variant.

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Data Gallery

Fig. 1.) SDS-PAGE analysis
On SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

Fig. 2.)    SEC-HPLC analysis
The purity of this product is more than 95% verified by SEC-HPLC.