This is a humanized IgG1 antibody using the same sequences as the therapeutic antibody nirsevimab. It is a monoclonal antibody with activity against the respiratory syncytial virus (RSV) fusion protein. RSV is a major cause of lower respiratory tract infection and hospitalization in infants. Nirsevimab is designed to bind the F1 and F2 subunits on the RSV’s surface at a highly conserved epitope and locks the RSV F protein in the prefusion conformation to block viral entry into the host cell. It has a modified Fc region, extending the half-life of the drug in order to last the whole RSV season.
Product name | Nirsevimab Biosimilar |
Species | Homo sapiens |
Expression system | CHO-K1 |
Buffer | PBS, pH 7.4 |
Delivery condition | Dry ice (-80°C) |
Delivery Time | 1 week if in stock; 4 weeks if production needed |
Storage condition | Store at -80°C |
Brand | BioMetas |
Applications | ELISA, assay, in vivo |
Aliases/Synonyms | Beyfortus®, MEDI8897, nirsevimab-alip |
Reference | |
Note | For research use only. Not suitable for clinical or therapeutic use. |
Isotype | IgG1 |
Clonality | Monoclonal Antibody |
Size | 1mg, 5mg, 10mg, 50mg, 100mg |
Brand | BioMetas |
Product type | Biosimilar |
Clonality | Monoclonal Antibody |
Expression system | CHO-K1 |
Applications | Elisa, assay, in vivo |
Amount | Price |
1mg | ¥1200 |
5mg | ¥3000 |
10mg | ¥5000 |
25mg | ¥7500 |
50mg | ¥10000 |
100mg | ¥15000 |
Fig. 1.) 4-20% SDS-PAGE analysis
Recombinant protein was visualized by Coomassie Brilliant Blue R250 staining.
Fig. 2.) SEC-HPLC analysis
Column: Superdex 200 Increase 5/150 GL
Running buffer: 2xPBS, pH 7.4