NRAS(2-186) Q61L
Description
NRAS is a member of the RAS gene family, and an oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor.
Product name | Recombinant Human NRAS protein |
Tag | His at N-terminus |
Amino Acids | 2 to 186 |
MW | 23351.37Da |
Species | Human |
Accession | P01111 |
Synonyms | Transforming protein N-Ras, GTPase NRas, HRAS1, NS6, ALPS4, NRAS1 |
Description | The recombinant NRAS protein, encompassing amino acids 2-186 (end), with Q61L mutation and N-terminal His-tag, expressed in a E.coli cell expression system. The protein is purified by using conventional chromatography techniques. |
Source | Escherichia coli |
Purity | >90.0% as determined by SDS-PAGE >95.0% as determined by SEC-HPLC |
Formulation | 20 mM HEPES, pH 7.5, 50 mM NaCl, and 20 mM MgCl2 |
Stability | At least 6 months at -80°C |
Delivery Time | 1 week if in stock; 4 weeks if production needed |
Reference | No |
Note | For research use only. Not suitable for clinical or therapeutic use. |
Size | 100ug, 500ug, 1mg, 5mg, 10mg |
Brand | BioMetas |
Clonality | Recombinant Protein |
Expression system | Escherichia coli |
Applications | SDS-PAGE, ELISA, Western Blot |
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Data Gallery
Fig. 1.) 4-20% SDS-PAGE analysis
On SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.
Fig. 2.) SEC-HPLC analysis
The purity of this product is more than 95% verified by SEC-HPLC.
