Sacituzumab

Description

Sacituzumab is a recombinant IgG1 kappa, humanized monoclonal antibody, targeting Trophoblast cell surface antigen 2 (TROP2). It is used for the synthesis of antibody-drug conjugates (ADC) drugs, approved for metastatic triple-negative breast cancer (mTNBC).

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Data Gallery

Fig. 1.) 4-20% SDS-PAGE analysis
Recombinant protein was visualized by Coomassie Brilliant Blue R250 staining.

Fig. 2.)    SEC-HPLC analysis
Column: Superdex 200 Increase 5/150 GL
Running buffer: 2xPBS, pH 7.4