Vedolizumab

Description

Vedolizumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with Integrin alpha4 and beta7. It is an integrin blocker and anti-inflammatory agent used to manage ulcerative colitis and Crohn’s disease in adults.

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Data Gallery

Fig. 1.) 4-20% SDS-PAGE analysis
Recombinant protein was visualized by Coomassie Brilliant Blue R250 staining.

Fig. 2.)    SEC-HPLC analysis
Column: Superdex 200 Increase 5/150 GL
Running buffer: 2xPBS, pH 7.4